Carnitor Injection for Dialysis Related Carnitine Deficiency

Carnitor^® Injection Corrects DCD, Which Can Improve Ejection Fraction (EF)^1,2

EF percentage in symptomatic patients before and after treatment (chart)

$Changes in left ventricular ejection fraction (LVEF) during levocarnitine therapy (chart)$

A progressive improvement in mean LVEF was observed throughout the study, increasing from 32.0% to 41.8% overall²

"The clinical status of the patients' heart failure also was reported to improve, leading the investigators to conclude that carnitine was useful as an adjuvant therapy for dialysis patients with LV dysfunction." ³

References: 1. van Es A, et al: Amelioration of cardiac function by L-carnitine administration in patients on haemodialysis. Contrib Nephrol 1992;98:28-35. 2. Romagnoli GF, et al: Beneficial effects of L-carnitine in dialysis patients with impaired left ventricular function: an observational study. Curr Med Res Opin 2002;18:172-175. 3. Pauly DF, Pepine CJ: The role of carnitine in myocardial dysfunction. Am J Kidney Dis 2003;41:S35-S43.

Carnitor® Injection Corrects DCD, Which Can Improve Ejection Fraction (EF)1,2

"The clinical status of the patients' heart failure also was reported to improve, leading the investigators to conclude that carnitine was useful as an adjuvant therapy for dialysis patients with LV dysfunction." 3

Carnitor^® Injection Corrects DCD, Which Can Improve Ejection Fraction (EF)^1,2

"The clinical status of the patients' heart failure also was reported to improve, leading the investigators to conclude that carnitine was useful as an adjuvant therapy for dialysis patients with LV dysfunction." ³